Peptiva Probiotics + Sleep Support Review: Pros, Cons, and More

The benefits of taking a probiotic supplement may be more than meets the eye. In order to get your money’s worth, you need to consider how well Peptiva performs in comparison with other products on the market and its additional features that are available.

Peptiva Probiotics + Sleep Support is a supplement that claims to provide relief from stress, anxiety, and insomnia. It also helps with weight loss and digestion. The company behind the product has been in court for some time now, but it’s still available online.


  • Several compounds have been scientifically shown to be useful.
  • It’s easy to use; you may take it with or without meals.
  • Allergen-free; vegan & vegetarian-friendly


  • When compared to other nocturnal probiotics, this one is a little more expensive.
  • To get the full advantages of this vitamin, you’ll need to take it for many months.
  • There isn’t a third-party testing label.

Peptiva Probiotics + Sleep Support: What Is It?

Peptiva Probiotics + Sleep Support is a product that promotes relaxation and sleep in adults while also supporting digestive health.

It includes GABA, melatonin, and valerian root, as well as a special probiotic combination.

Peptiva Probiotics + Sleep Support should be taken once a day, 30 to 60 minutes before bedtime.

It is possible to take this supplement with or without meals. However, it is advised that you take it with a little snack for better digestive comfort.

Sleep and relaxation effects may be noticed within 30 minutes, but digestion benefits will likely take 8 to 12 weeks of constant usage.

Dr. David Katz, a preventive medicine expert and former director and co-founder of the Yale Prevention Research Center, helped develop and select the probiotic strains utilized in Peptiva Probiotics products.


Ingredients Evaluation

Peptiva Probiotics + Sleep Support has a total of 26 billion CFUs in its probiotic combination.

Because this is a custom mix, determining whether probiotics are present in clinically active concentrations is challenging.

It’s also worth noting that a probiotic strain’s impact is strain-specific, meaning it can’t be generalized to other strains from the same genus, or even to strains from the same species and sub-species.

With this in mind, research on related species has been considered for strains that do not have accessible clinical data.

Lactobacillus acidophilus is a kind of probiotic bacteria (ATCC SD6865 and SD6866)

The most often utilized probiotic for intestinal health is Lactobacillus acidophilus.

This bacterium improves gastrointestinal function, decreases gut inflammation, and may enhance gut bacterial balance.

After four weeks, consuming L. acidophilus twice daily relieved symptoms of bloating in people with digestive diseases, according to one research investigation.

Bifidobacterium bifidum (Bifidobacterium bifidum) (ATCC SD6869)

One of the earliest forms of bacteria detected in the baby gastrointestinal system is B. bifidum, which is believed to strengthen the gut.

Patients with IBS symptoms were given a placebo or a B. bacteria strain (MIMBb75) once a day for four weeks in a randomized experiment.

Patients reported a substantial improvement in pain, bloating, digestive issues, and bowel control at the conclusion of the experiment when compared to a control group.

Bifidobacterium animalis subsp. lactis is a kind of Bifidobacterium (ATCC SD6870)

By lowering gut dysbiosis, or an imbalance of bacteria in the gut, B. animalis has been shown to enhance gut microbiota and general health.

When compared to a placebo, B. lactis UABla-12 supplementation for six weeks reduced stomach discomfort, bloating, bowel habits, and quality of life in persons with IBS, according to one randomized study.

Lactobacillus rhamnosus is a kind of lactobacillus (IMC 501)

L. rhamnosus has the ability to protect digestive cells while also reducing inflammation.

According to research, L. rhamnosus strains are beneficial in treating diarrhea in a variety of illnesses, including cancer treatment-related diarrhea, antibiotic-related diarrhea, and C. diff colitis.

SYNBIO is a probiotic that contains both Lactobacillus rhamnosus IMC 501 and Lactobacillus paracasei IMC 502.

Healthy people got this probiotic in enhanced meals or pills in a 2014 clinical study. After 12 weeks, compared to placebo, SYNBIO improved bowel movement regularity, stool volume and consistency, health-related quality of life, bloating, and constipation.

Lactobacillus paracasei is a kind of lactobacillus (IMC 502)

L. paracasei is a kind of bacterium that may be found in the human body as well as milk and other dairy products.

For eight weeks, people with various forms of IBS were given L. paracasei, B. longum, or a placebo in a study.

The GI symptoms of those who got a probiotic improved. Those who were given L. paracasei had more frequent bowel movements and a higher quality of life.

In addition to its intestinal health advantages, cell tests reveal that SYNBIO has antimicrobial activity and the ability to fight wound infections like those present in chronic ulcers.

50 milligrams Valerian Root Extract

Valerian is a blooming plant native to Europe and Asia, and its roots are often used as a natural sleep aid.

While some of the data on the advantages is contradictory, a review and meta-analysis of 60 studies revealed that valerian root may help with sleep quality and anxiety reduction.

100 mg Gamma-Aminobutyric Acid (from PharmaGABA)

GABA (gamma-aminobutyric acid) is a neurotransmitter and an amino acid.

GABA promotes slow-wave sleep and reduces waking (the stage associated with sleep quality and sleep restoration).

It was discovered that taking GABA alone or in combination with Apocynum venetum leaf extract reduced the time it took to fall asleep and increased slow-wave sleep.

1.5 mg melatonin (delayed and immediate release)

Melatonin is a hormone produced by the pineal gland that aids in the regulation of the brain’s circadian rhythms.

In research, this hormone has been proven to be beneficial in the treatment of sleep problems such as insomnia, sleep-related respiratory issues, and other ailments.

It may assist people enhance the beginning, length, and quality of their sleep.

Conclusion on Benefits Claimed

Based on the current research, the following is our summary of the available evidence for the stated advantages of Peptiva Probiotics + Sleep Support:

Supports the digestive system. There is There is Strong Evidence
Bloating, indigestion, and constipation are relieved. There is There is Strong Evidence
Supports sleep and relaxation. Evidence with a Gold Star


Safety and Side Effects

Adults should take Peptiva Probiotics + Sleep Support. Unfortunately, there was no information available on whether or not this product was safe for anyone under the age of 18.

While the producers claim there are no negative effects from using this product, some people may suffer melatonin or valerian side effects.

Morning tiredness, dizziness, nausea, headache, sleep-related adverse effects (including vivid dreams), and hypothermia are the most prevalent side effects of melatonin usage.

Valerian has no known major adverse effects, however it might induce minor side effects such as vivid dreams, weariness, sleepiness, gastrointestinal issues, dizziness, and depression in some individuals.

When you first start taking probiotics, you may have moderate side effects such as increased gas and bloating.

Before starting a new supplement, like with any other, it’s best to speak with a healthcare professional.

Individuals using antibiotics or corticosteroids may encounter problems or get less benefits from the probiotic, according to Peptiva.

Because there is insufficient data on the safety of some constituents (such valerian) during pregnancy, pregnant or nursing women should contact with their doctor before using this supplement.

Valerian use during pregnancy was shown to lower zinc and copper levels in embryonic brain tissue in a 2012 animal research.

There are no recognized significant allergies in Peptiva Probiotics + Sleep Support. This supplement is cruelty-free.

The corporation claims that its laboratories are GMP-certified, however there is no mention of extra third-party testing on the Peptiva website.

Where to Buy and How Much

Peptiva products may be found on the company’s website, as well as through GNC, Walmart, and Amazon.

Peptiva Probiotics + Sleep Support costs $49.99–$59.99 a month, depending on the vendor.

Peptiva provides a 15-day sample trial on their website if you don’t want to commit to buying a full bottle of the supplement.

When you sign up for a trial, you are also signing up for a product subscription. If you don’t enjoy Peptiva Probiotics + Sleep Support, you may cancel your subscription by calling their customer care number.

If you are not totally happy with your purchase, Peptiva offers a 30-day money-back guarantee.

The pricing of Peptiva Probiotics + Sleep Support is fair, given that it contains a sleep supplement and a probiotic.

Peptiva is available for purchase on Amazon.

How Does Peptiva Probiotic + Sleep Support Measure Up to the Competition?

There aren’t many probiotics available for use at night. Peptiva Probiotic + Sleep Support is more costly than its rivals out of the ones I looked at.

Despite its high price, it has certain benefits over its competitors.

Some nocturnal probiotics only included one beneficial strain of bacteria, did not contain melatonin, or had a reduced total concentration of bacteria colonies.

Dietitians’ Picks for the Best Probiotics in 2022

Final Thoughts

Peptiva Probiotic + Sleep Support looks to be a well-designed nighttime probiotic in general.

Clinical research have been conducted on several of the substances to back up the claims made in this product.

Because some of the strains lack clinical data, the probiotic combination has certain limits, and I’d want to see additional study on them.

Peptiva Probiotic + Sleep Support is very easy to use, with little side effects or interactions for the majority of consumers.

This pill looks to be an effective adjunct to a healthy lifestyle for gut and sleep support.

A Message from Our RD

To enhance one’s overall health, I feel it is critical that individuals take care of their gut and sleep quality.

Probiotic pills may aid in the maintenance of a healthy gut flora. It’s worth noting, though, that oral probiotics must be taken on a regular basis to be effective, and the advantages may fade if you stop taking them.

Probiotic-rich foods such as yogurt, fermented cabbage, and kefir may help to maintain gut health over time.

Various fruits, vegetables, and whole grains include beneficial prebiotics that feed good bacteria and help them flourish.

In terms of sleep health, I sometimes drink valerian root tea to help me sleep. This is not, however, a replacement for other sleep hygiene practices.

Plan your day such that you receive 7–9 hours of sleep at night to improve your health.

Creating a calm and pleasant setting, limiting exposure to blue light or bright displays before bed, and undertaking soothing activities in the hour before sleep are all crucial sleep practices.


Watch This Video-

Peptiva is a probiotic supplement that promises to support your sleep. The company claims that it has the “best ingredients” and is gluten-free. It also comes with a 60 day money back guarantee. Reference: how to cancel peptiva.

Frequently Asked Questions

What are the negative side effects of taking probiotics?

A: Side effects of taking probiotics are not too many, but the most common side effect is that it can cause gas.

Does Peptiva really help you sleep?

A: Yes, it essentially sends serotonin to the brain and helps you sleep.

Can taking probiotics daily be harmful?

A: If you have any concerns or questions regarding your health, please consult with a doctor before taking probiotics.

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